Rafael Moreno-Sánchez Selected Research

Celecoxib (Celebrex)

1/2022	Celecoxib and Dimethylcelecoxib Block Oxidative Phosphorylation, Epithelial-Mesenchymal Transition and Invasiveness in Breast Cancer Stem Cells.
12/2020	Non-Steroidal Anti-Inflammatory Drugs Increase Cisplatin, Paclitaxel, and Doxorubicin Efficacy against Human Cervix Cancer Cells.
11/2019	Repurposing drugs as pro-oxidant redox modifiers to eliminate cancer stem cells and improve the treatment of advanced stage cancers.
1/2018	Celecoxib inhibits mitochondrial O2 consumption, promoting ROS dependent death of murine and human metastatic cancer cells via the apoptotic signalling pathway.
1/2018	Energy Metabolism Drugs Block Triple Negative Breast Metastatic Cancer Cell Phenotype.

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Rafael Moreno-Sánchez Research Topics

Disease

48	Neoplasms (Cancer) 01/2023 - 06/2003
10	Hepatocellular Carcinoma (Hepatoma) 11/2020 - 06/2003
10	Hypoxia (Hypoxemia) 01/2018 - 08/2009
8	Breast Neoplasms (Breast Cancer) 01/2022 - 03/2013
6	Carcinoma (Carcinomatosis) 01/2022 - 12/2009
5	Neoplasm Metastasis (Metastasis) 11/2019 - 02/2015
4	Carcinogenesis 11/2019 - 10/2007
3	Uterine Cervical Neoplasms (Cancer of the Cervix) 12/2020 - 08/2015
3	Hypoglycemia (Reactive Hypoglycemia) 10/2017 - 08/2014
2	Chromate Resistance 09/2009 - 07/2002
2	Heart Diseases (Heart Disease) 10/2007 - 03/2003
1	Colorectal Neoplasms (Colorectal Cancer) 01/2021
1	Dysbiosis 01/2021
1	Colonic Neoplasms (Colon Cancer) 01/2021
1	Chagas Disease (American Trypanosomiasis) 01/2019
1	Polyps 01/2019
1	Hand-Foot Syndrome 01/2018
1	Melanoma (Melanoma, Malignant) 01/2018
1	Ascites 01/2016

Drug/Important Bio-Agent (IBA)

18	Adenosine Triphosphate (ATP)IBA 01/2023 - 03/2003
18	Proteins (Proteins, Gene)FDA Link 01/2022 - 09/2009
16	EnzymesIBA 11/2020 - 03/2003
10	Glucose (Dextrose)FDA LinkGeneric 11/2020 - 03/2003
8	HexokinaseIBA 01/2016 - 05/2006
6	GlycogenIBA 11/2020 - 11/2010
6	Succinic Acid (Succinate)IBA 01/2019 - 06/2003
5	OligomycinsIBA 01/2023 - 06/2003
5	Celecoxib (Celebrex)FDA Link 01/2022 - 01/2018
5	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 12/2020 - 01/2009
5	IsomerasesIBA 11/2020 - 05/2014
4	Transcription Factors (Transcription Factor)IBA 01/2022 - 08/2009
4	Biomarkers (Surrogate Marker)IBA 11/2019 - 10/2011
4	casiopeina II-glycineIBA 01/2018 - 09/2006
4	Facilitative Glucose Transport Proteins (Glucose Transporter)IBA 01/2016 - 08/2009
4	Protein Isoforms (Isoforms)IBA 08/2014 - 08/2009
4	Oxygen (Dioxygen)IBA 08/2013 - 08/2009
3	Cisplatin (Platino)FDA LinkGeneric 12/2020 - 01/2009
3	Paclitaxel (Taxol)FDA LinkGeneric 12/2020 - 01/2009
3	Doxorubicin (Adriamycin)FDA LinkGeneric 12/2020 - 01/2009
3	NADP (NADPH)IBA 11/2020 - 11/2017
3	Adenosine Diphosphate (ADP)IBA 01/2020 - 07/2008
3	Phosphates (Orthophosphate)IBA 01/2019 - 06/2014
3	GossypolIBA 06/2017 - 09/2006
3	Messenger RNA (mRNA)IBA 01/2016 - 10/2010
3	Lactic Acid (Lactate)FDA LinkGeneric 06/2014 - 05/2012
3	alpha-Tocopherol FDA Link 02/2013 - 02/2011
3	Antineoplastic Agents (Antineoplastics)IBA 05/2012 - 04/2006
2	Reactive Oxygen Species (Oxygen Radicals)IBA 11/2019 - 11/2011
2	AntioxidantsIBA 01/2019 - 02/2015
2	Glutathione Disulfide (GSSG)FDA LinkGeneric 10/2018 - 11/2017
2	TeaIBA 01/2018 - 09/2012
2	Lactate Dehydrogenase 5IBA 01/2018 - 08/2009
2	CytokinesIBA 10/2017 - 06/2014
2	6-phosphogluconic acidIBA 10/2017 - 06/2014
2	Oxidoreductases (Dehydrogenase)IBA 01/2016 - 06/2003
2	Pyruvate KinaseIBA 01/2016 - 08/2014
2	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 01/2016 - 05/2006
2	Phosphofructokinase-1 (Phosphofructokinase 1)IBA 05/2014 - 05/2006
2	Glutamine (L-Glutamine)FDA Link 05/2014 - 09/2006
2	Fatty Acids (Saturated Fatty Acids)IBA 05/2014 - 03/2003
2	Ketoglutaric Acids (Ketoglutaric Acid)IBA 05/2014 - 06/2003
2	Vitamin E FDA LinkGeneric 09/2012 - 11/2011
2	CopperIBA 05/2012 - 04/2006
2	Hypoglycemic Agents (Hypoglycemics)IBA 06/2011 - 10/2007
2	Electron Transport Complex IV (Cytochrome c Oxidase)IBA 10/2010 - 08/2009
2	ChromatesIBA 09/2009 - 07/2002
1	Hormones (Hormone)IBA 01/2022
1	Estradiol (Delestrogen)FDA LinkGeneric 01/2022
1	Acetates (Acetic Acid Esters)FDA Link 01/2021
1	Carboxylic AcidsIBA 01/2021
1	PhosphoglucomutaseIBA 11/2020
1	Leucine (L-Leucine)FDA Link 01/2020
1	Glutamate DehydrogenaseIBA 01/2020
1	Auranofin (Ridaura)FDA Link 11/2019
1	Protein Kinases (Protein Kinase)IBA 10/2019
1	Ataxia Telangiectasia Mutated ProteinsIBA 03/2019
1	Phosphotransferases (Kinase)IBA 03/2019
1	trypanothioneIBA 01/2019
1	ResveratrolIBA 01/2019
1	MetalsIBA 01/2019
1	PeroxidesIBA 01/2019
1	PolyphosphatesIBA 01/2019
1	Sulfhydryl Compounds (Thiols)IBA 01/2019
1	Superoxides (Superoxide)IBA 01/2018
1	Capecitabine (Xeloda)FDA Link 01/2018
1	Aminooxyacetic AcidIBA 01/2017
1	Dihydroxyacetone PhosphateIBA 01/2016
1	Phosphoglycerate Kinase (Kinase, Phosphoglycerate)IBA 01/2016
1	Phosphopyruvate Hydratase (Enolase)IBA 01/2016
1	HexosesIBA 01/2016
1	CholesterolIBA 08/2015
1	NAD (NADH)IBA 08/2015
1	PerhexilineIBA 08/2015
1	Nonesterified Fatty Acids (NEFA)IBA 08/2015
1	Mitochondrial Permeability Transition PoreIBA 02/2015
1	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 02/2015
1	Cadherins (E-Cadherin)IBA 12/2014

Therapy/Procedure

14	Therapeutics 01/2022 - 10/2007
4	Drug Therapy (Chemotherapy) 11/2019 - 03/2007
1	Immunotherapy 11/2019